The Lyon's Whelp left the Thames, Gravesend, England April 5, 1629 along with five other ships, George Bonaventure, Four Sisters, Lyon, the Mayflower and the Talbot, arriving  in Salem June 1629.

Known Passengers:

Thomas Minor
Simon HOYT (http://freepages.genealogy.rootsweb.com/~robinsgenealogypage/index.html)

“Now in this year1629, a great company of people (The Higginson Fleet) of good rank, zeal, means and quality have made a great stock, and with six good ships in the months of April and May, they set sail from Thames for the Bay of the Massachusetts, otherwise called Charles River.  The fleet consisted of, the George Bonaventure of twenty pieces of ordnance; the Talbot nineteen; the Lion’s Whelp eight; the Mayflower fourteen; the Four sisters fourteen and the Pilgrim four, with 350 men women and children, also 115 head of cattle, as horses, mares, cows and oxen, 41 goats, some conies (rabbits), with all provision for household and apparel, 6 pieces of great ordnance for a fort, with muskets, pikes, corselets, drums, colors, and with all provisions necessary for a plantation for the good of man.”
(The True Travels, Adventures and Observations of Captain John Smith – London 1630)

From http://users.adelphia.net/~cousin.wes3/stower_stowers_history.htm

Charles Banks Topo lists the following passengers:
Eedes, William, from Dorsethsire, bound for Salem. Ref: Hist Record of Putman Co, NY. 36 pg 37.
Hoyt, Simon, from Upway, bound for Charlestown and Salem, Dorchester, Windsor Ct. Ref: Hist Record of Putman Co, NY. Notation states he was aboard to Lions Whelp or the Abigail, 1629. 36 pg 36.
Sprague, Ralph, Richard and William, all from Upway, Dorsetshire, bound for Salem 169. Ref: Pope. 36 pg 35.
Stower, first name unknown, from Upway, Dorsetshire, bound for Charlestown, MA 1629.
Tilly, Hugh, from Somersetshire, bound for Salem and Yarmouth. Ref: Mass Col Rec 1/101. 36 pg 147.
Lyon's Whelp sources:
http://www.sprague-database.org
http://www.stoningtonhistory.org/archiv4.htm

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research and compilation was done by Anne Stevens of packrat-pro.com

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